Possible signs of neuroblastoma include bone pain and a lump in the abdomen, neck, or chest.

The most common symptoms of neuroblastoma are caused by the tumor pressing on nearby tissues as it grows or by cancer spreading to the bone. These and other symptoms may be caused by neuroblastoma. Other conditions may cause the same symptoms. A doctor should be consulted if any of the following problems occur:

• Lump in the abdomen, neck, or chest.
• Bulging eyes.
• Dark circles around the eyes (”black eyes”).
• Bone pain.
• Swollen stomach and trouble breathing in infants.
• Painless, bluish lumps under the skin in infants.
• Weakness or paralysis (loss of ability to move a body part).

Less common signs of neuroblastoma include the following:

• Fever.
• Shortness of breath.
• Feeling tired.
• Easy bruising or bleeding.
• Petechiae (flat, pinpoint spots under the skin caused by bleeding).
• High blood pressure.
• Severe watery diarrhea.
• Jerky muscle movements.
• Uncontrolled eye movement.
• Swelling of the legs, ankles, feet, or scrotum.

Information from: The Web site of the National Cancer Institute (http://www.cancer.gov)